21C Museum Hotel St Louis in St. Louis

9/10 from 2126 reviews

Amenities

Fitness facilities
Free WiFi

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Where you'll be

Choose your room

Check in

Oct 12th 2026

Check out

Oct 13th 2026

Travelers

2 adults

Deluxe Room, 1 King Bed
309 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Luxury Double Room, 2 Queen Beds
423 sq ft
Fitness facilities
Free WiFi
Sleeps 4
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Room (Bunk Bed)
237 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Loft, 2 Queen Beds
431 sq ft
Fitness facilities
Free WiFi
Sleeps 4
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Deluxe Room, Accessible (Accessible)
269 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Suite, 1 King Bed (21C)
1119 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Suite, 1 King Bed (Library)
732 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Luxury Suite, 1 King Bed
549 sq ft
Fitness facilities
Free WiFi
Sleeps 2
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Deluxe Room, 1 Double Bed, Accessible
388 sq ft
Fitness facilities
Free WiFi
Sleeps 4
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Deluxe Suite, 1 Double Bed, Accessible
517 sq ft
Fitness facilities
Free WiFi
Sleeps 2
More details

About this property

21C Museum Hotel St Louis

A stay at 21C Museum Hotel St Louis places you in the heart of St. Louis, within a 10-minute walk of Enterprise Center and St. Louis Union Station. This luxury hotel is 0.3 mi (0.4 km) from City Museum and 0.7 mi (1.1 km) from America's Center Convention Complex.

Languages

English

Policies

Check-in

Check-in between 4:00 PM - 11:00 AM

Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property. Information provided by the property may be translated using automated translation tools.

Other instructions

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and outdoor lighting

Property payment types

American Express, Mastercard, Visa, Cash not accepted, Debit cards not accepted

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
Valet parking fee: USD 55 per day (in/out privileges)
Pet fee: USD 100 per accommodation, per stay
Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Reservations are required for massage services. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Other information

General

No rollaway/extra beds available
No cribs (infant beds) available
Green Key Global
LGBTQIA+ friendly
Professional property host/manager

Pets

Pets allowed
Only dogs are allowed
Service animals are allowed
Service animals are exempt from fees/restrictions